USC-OGP 2-DE database Two-dimensional polyacrylamide gel electrophoresis database

USC-OGP 2-DE database  Search by                Maps             Select Remote Interfaces [All Interfaces] SWISS-2DPAGE World-2DPAGE Portal World-2DPAGE Repository Exclude local DBs has only effect if a remote interface is selected

Searching in 'USC-OGP 2-DE database' for entry matching: NEXN_HUMAN USC-OGP 2-DE database:  NEXN_HUMAN NEXN_HUMAN General information about the entry View entry in simple text format Entry name NEXN_HUMAN Primary accession number Q0ZGT2 Secondary accession number(s) Q16081 integrated into USC-OGP 2-DE database on  January 17, 2017 (release 1) 2D Annotations were last modified on January 17, 2017 (version 1) General Annotations were last modified on  April 5, 2017 (version 2) Name and origin of the protein Description RecName: Full=Nexilin; AltName: Full=F-actin-binding protein; AltName: Full=Nelin;. Gene name Name=NEXN {ECO:0000312|HGNC:HGNC:29557} Annotated species Homo sapiens (Human) [TaxID: 9606] Taxonomy Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo. References [1]   2D GEL CHARACTERIZATION Author 1., Author 2. Submitted (Mar-2011) to Current 2D PAGE maps for identified proteins How to interpret a protein PLATELET_4-7 {PLATELET 4-7} Homo sapiens (Human)   map experimental info   PLATELET_4-7 MAP LOCATIONS: SPOT OGP-0289: pI=5.05; Mw=96639 Cross-references UniProtKB/Swiss-Prot Q0ZGT2; NEXN_HUMAN. 2D PAGE maps for identified proteins How to interpret a protein map You may obtain an estimated location of the protein on various 2D PAGE maps, provided the whole amino acid sequence is known. The estimation is obtained according to the computed protein's pI and Mw. Warning 1: the displayed region reflects an area around the theoretical pI and molecular weight of the protein and is only provided for the user's information. It should be used with caution, as the experimental and theoretical positions of a protein may differ significantly. Warning 2: the 2D PAGE map is built on demand. This may take some few seconds to be computed. External data extracted from UniProtKB/Swiss-Prot Extracted from UniProtKB/Swiss-Prot, release: 0.0 Entry name NEXN_HUMAN Primary accession number Q0ZGT2 Secondary accession number(s) A0PJ84 B4DPZ7 Q0D2H2 Q14CC2 Q14CC3 Q16081 Q7Z2X0 Q96DL0 Q9Y2V1 Sequence was last modified on  August 22, 2006 (version 1) Annotations were last modified on  March 15, 2017 (version 109) Name and origin of the protein Description RecName: Full=Nexilin; AltName: Full=F-actin-binding protein; AltName: Full=Nelin; Gene name Name=NEXN {ECO:0000312|HGNC:HGNC:29557} Encoded on Name=NEXN {ECO:0000312|HGNC:HGNC:29557 Keywords Actin-binding; Alternative splicing; Cardiomyopathy; Cell junction; Complete proteome; Cytoplasm; Cytoskeleton; Disease mutation; Immunoglobulin domain; Phosphoprotein; Polymorphism; Reference proteome. Copyright Copyrighted by the UniProt Consortium, see http://www.uniprot.org/help/license. Distributed under the Creative Commons Attribution-NoDerivs License Cross-references EMBL DQ464902; ABE97925.1; -; mRNA EMBL AK057954; BAB71622.1; ALT_INIT; mRNA EMBL AK298565; BAG60759.1; -; mRNA EMBL AC096948; -; NOT_ANNOTATED_CDS; Genomic_DNA EMBL AC138392; -; NOT_ANNOTATED_CDS; Genomic_DNA EMBL BC055084; AAH55084.1; ALT_SEQ; mRNA EMBL BC017827; AAH17827.1; ALT_SEQ; mRNA EMBL BC111395; AAI11396.1; ALT_INIT; mRNA EMBL BC114444; AAI14445.1; ALT_INIT; mRNA EMBL BC114445; AAI14446.1; ALT_INIT; mRNA EMBL AF114264; AAD29607.1; -; mRNA EMBL S67069; AAB28815.1; -; mRNA CCDS CCDS41351.1; -. [Q0ZGT2-1]; . CCDS CCDS53335.1; -. [Q0ZGT2-4]; . RefSeq NP_001165780.1; NM_001172309.1. [Q0ZGT2-4]; . RefSeq NP_653174.3; NM_144573.3. [Q0ZGT2-1]; . RefSeq XP_005271380.1; XM_005271323.3. [Q0ZGT2-2]; . UniGene Hs.612385; -; . ProteinModelPortal Q0ZGT2; -; . SMR Q0ZGT2; -; . BioGrid 124855; 48; . IntAct Q0ZGT2; 36; . MINT MINT-8187852; -; . STRING 9606.ENSP00000333938; -; . iPTMnet Q0ZGT2; -; . PhosphoSitePlus Q0ZGT2; -; . BioMuta NEXN; -; . DMDM 121945484; -; . EPD Q0ZGT2; -; . MaxQB Q0ZGT2; -; . PaxDb Q0ZGT2; -; . PeptideAtlas Q0ZGT2; -; . PRIDE Q0ZGT2; -; . Ensembl ENST00000330010; ENSP00000327363; ENSG00000162614. [Q0ZGT2-4]; . Ensembl ENST00000334785; ENSP00000333938; ENSG00000162614. [Q0ZGT2-1]; . GeneID 91624; -; . KEGG hsa:91624; -; . UCSC uc001dib.5; human. [Q0ZGT2-1]; . CTD 91624; -; . DisGeNET 91624; -; . GeneCards NEXN; -; . GeneReviews NEXN; -; . HGNC HGNC:29557; NEXN; . HPA HPA011185; -; . MalaCards NEXN; -; . MIM 613121; gene; . MIM 613122; phenotype; . MIM 613876; phenotype; . neXtProt NX_Q0ZGT2; -; . OpenTargets ENSG00000162614; -; . Orphanet 154; Familial isolated dilated cardiomyopathy; . Orphanet 155; Familial isolated hypertrophic cardiomyopathy; . PharmGKB PA134974801; -; . eggNOG ENOG410IF6R; Eukaryota; . eggNOG ENOG4110P6X; LUCA; . GeneTree ENSGT00730000111176; -; . HOVERGEN HBG066529; -; . InParanoid Q0ZGT2; -; . OMA FHEEEDV; -; . OrthoDB EOG091G06IR; -; . PhylomeDB Q0ZGT2; -; . TreeFam TF328960; -; . ChiTaRS NEXN; human; . GenomeRNAi 91624; -; . PRO PR:Q0ZGT2; -; . Proteomes UP000005640; Chromosome 1; . Bgee ENSG00000162614; -; . CleanEx HS_NEXN; -; . ExpressionAtlas Q0ZGT2; baseline and differential; . Genevisible Q0ZGT2; HS; . GO GO:0005856; C:cytoskeleton; IEA:UniProtKB-SubCell; . GO GO:0005925; C:focal adhesion; IDA:UniProtKB; . GO GO:0030018; C:Z disc; ISS:UniProtKB; . GO GO:0051015; F:actin filament binding; IDA:UniProtKB; . GO GO:0008307; F:structural constituent of muscle; IMP:UniProtKB; . GO GO:0048739; P:cardiac muscle fiber development; IBA:GO_Central; . GO GO:0030334; P:regulation of cell migration; IDA:UniProtKB; . GO GO:0051493; P:regulation of cytoskeleton organization; IEP:UniProtKB; . Gene3D 2.60.40.10; -; 1; . InterPro IPR007110; Ig-like_dom; . InterPro IPR013783; Ig-like_fold; . InterPro IPR013098; Ig_I-set; . InterPro IPR003599; Ig_sub; . Pfam PF07679; I-set; 1; . SMART SM00409; IG; 1; . SUPFAM SSF48726; SSF48726; 1; . PROSITE PS50835; IG_LIKE; 1; .

Gateways to other related servers

• The World-2DPAGE Constellation - Entry point to the world-wide 2-DPAGE resources.
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• World-2DPAGE Portal - A dynamic portal to query simultaneously world-wide gel-based proteomics databases.
• SWISS-2DPAGE - The Geneva Two-dimensional polyacrylamide gel electrophoresis database.
• ExPASy - The resources web server of the Swiss Institute of Bioinformatics

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